Is there room for independent retailers in an American landscape littered with big-box corporate chain stores? Husband and wife TV-news veterans Hanson Hosein and Heather Hughes set out on an epic, 32-state cross-country road trip to see how independent businesses are faring. Their rules: avoid interstate highways and try to patronize only locally owned establishments. In, the process they discover stories of ingenuity, self-reliance, community activism and a growing nationwide opposition to corporate uniformity.